App unresponsive when javascript-profiling them

For a while I've been trying to run a JavaScript CPU profile of some applications I've developed, but everytime I start running the JavaScript CPU profiler in Chrome Dev tools, the application will stop responding at all (same as the profiler).

However, I noticed that this is not specific to my application, since I've been able to reproduce the same problem in other popular applications like Travis-CI.

I've been suspecting of extensions and plugins, but running without them doesn't seem to make a different -- the problem persists.

I've tested simpler apps with the same technology (the To-Do MVC example built in EmberJS) and that profile works just as fine.

I'm currently using Chrome 40.0.2214.111 m (64-bit).

Any idea on what the problem may be?